Drug – bio-affecting and body treating compositions – Whole live micro-organism – cell – or virus containing
Patent
1995-06-05
1998-12-01
Chambers, Jasemine C.
Drug, bio-affecting and body treating compositions
Whole live micro-organism, cell, or virus containing
435331, 435 71, 424 9321, C12N 500, A61K 3900
Patent
active
058434259
ABSTRACT:
A method of preparing swine donor tissue which includes hematopoietic stem cells and T cells for transplantation into a recipient mammal other than a swine. The method includes the swine donor tissue with an antibody which binds the epitope recognized by the mAb 2-6-15 monoclonal antibody. The binding facilitates depletion of T cells about as efficiently or more efficiently than does the mAb 2-6-15 monoclonal antibody and results in about the same or less depletion of stem cells as does the mAb 2-6-15 monoclonal antibody.
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Arn J. Scott
Lorf Thomas
Sachs David H.
Chambers Jasemine C.
Hauda Karen M.
The General Hospital Corporation
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