Transplantable artificial tissue and process

Details Transplantable artificial tissue and process Transplantable artificial tissue and process

1989-12-04

1991-03-05

Cannon, Alan W.

Prosthesis (i.e., artificial body members), parts thereof, or ai

Implantable prosthesis

623 66, 435177, 435182, A61F 202, C12N 1102

Patent

active

049974432

ABSTRACT:
A transplantable artificial tissue matrix structure containing viable cells which is suitable for insertion into the body is made by polymerizing precursors in an aqueous solution to form a shape retaining solid matrix comprising viable cells, matrix polymer and reversible gel polymer. The solution contains a matrix polymer precursor, a reversible gel polymer precursor, and viable cells. The reversible gel polymer is dissolved and removed to yield an insoluble, porous matrix containing viable cells. The conditions and reagents are selected to maintain the viability of the cells. The invention is particularly suitable for artificial transplant matrix tissue containing pancreatic islet cells.

REFERENCES:
patent: 4504582 (1985-03-01), Swann
patent: 4526867 (1985-07-01), Chibata et al.
patent: 4645669 (1987-02-01), Reid
patent: 4647536 (1987-03-01), Mosbach et al.
patent: 4689293 (1987-08-01), Goosen et al.
patent: 4722898 (1988-02-01), Errede et al.
patent: 4798786 (1989-01-01), Tice et al.
patent: 4861714 (1989-08-01), Dean, Jr. et al.

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