Prosthesis (i.e. – artificial body members) – parts thereof – or ai – Implantable prosthesis – Bone
Reexamination Certificate
2006-01-24
2006-01-24
Marx, Irene (Department: 1651)
Prosthesis (i.e., artificial body members), parts thereof, or ai
Implantable prosthesis
Bone
C623S023610, C424S423000, C424S422000, C435S395000, C435S325000
Reexamination Certificate
active
06989030
ABSTRACT:
A transplant material which is capable of imparting desired mechanical properties, elevating bone tissue repair speed and improving biocompatibility. This transplant material comprises an artificial and biologically inactive material, which is to be implanted in vivo as a substitute for bone tissue, and at least one type of cells selected from among osteoblasts and precursory osteoblasts which are adhered to the surface of the artificial material so that the artificial material is coated with the bone matrix produced by the cells. The artificial material involves not only a biologically inactive material but also a biologically inactive material coated with a biologically active substrate. This transplant material is produced by culturing mesenchymal stem cells collected from a living body to differentiate into at least one type of cells selected from among osteoblasts and precursory osteoblasts and then culturing the cells together with the artificial material to thereby adhere the differentiated cells on the surface of the artificial material and coat the surface of the artificial material with the bone matrix produced by the differentiated cells.
REFERENCES:
patent: 2679245 (1954-05-01), Timmermans
patent: 4164794 (1979-08-01), Spector et al.
patent: 4878914 (1989-11-01), Miwa et al.
patent: 5306305 (1994-04-01), Lee
patent: 5643789 (1997-07-01), Ducheyne et al.
patent: 6541024 (2003-04-01), Kadiyala et al.
patent: 03-045267 (1991-02-01), None
patent: 07-116184 (1995-05-01), None
patent: 08-112341 (1996-05-01), None
patent: WO 93/25246 (1993-12-01), None
patent: WO 94/04657 (1994-03-01), None
patent: WO 97/05238 (1997-02-01), None
patent: WO 97/40137 (1997-10-01), None
Nijweide et al., 1982. Bone formation and calcification by isolated osteoblastlike cells. J. Cell Biol. 93: 318-323.
Pittenger et al., 1999. Multilineage potential of adult human mesenchymal stem cells. Science 284: 143-147.
Mackie EJ. 2003. Osteoblasts: novel roles in orchestration of skeletal architecture. Int J Biochem Cell Bio 35: 1301-1305.
Barnhart Lora E
Fish & Richardson P.C.
Japan Tissue Engineering Co., Ltd.
Marx Irene
LandOfFree
Transplant material and method for fabricating the same does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Transplant material and method for fabricating the same, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Transplant material and method for fabricating the same will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3581350