Transnasal anticonvulsive compositions and modulated process

Details Transnasal anticonvulsive compositions and modulated process Transnasal anticonvulsive compositions and modulated process

2006-11-07

2006-11-07

Channavajjala, Lakshmi (Department: 1615)

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Implant or insert

C424S045000

Reexamination Certificate

active

07132112

ABSTRACT:
A novel method of vehicle modulated administration of an anticonvulsive agent to the mucous membranes of humans and animals is disclosed. The vehicle system is an aqueous pharmaceutical carrier comprising an aliphatic alcohol (10–80%) or a glycol (10–80%), and their combinations with a biological surfactant such as a bile salt or a lecithin. The pharmaceutical composition provides a means to control and promote the rate and extent of transmucosal permeation and absorption of the medicaments via a single and multiple administration. Nasal administration of the pharmaceutical preparation produces a high plasma concentration of the anticonvulsant nearly as fast as intravenous administration. Such compositions are particularly suitable for a prompt and timely medication of patients in the acute and/or emergency treatment of status epilepticus and other fever-induced seizures.

REFERENCES:
patent: 4863720 (1989-09-01), Burghart et al.
patent: 4950664 (1990-08-01), Goldberg
patent: 5428006 (1995-06-01), Bechgaard et al.
patent: 6627211 (2003-09-01), Choi et al.
patent: WO 91/16929 (1991-11-01), None
Supplementary European Search Report, Nov. 29, 2004.

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