Transmembrane protein differentially expressed in cancer

Details Transmembrane protein differentially expressed in cancer Transmembrane protein differentially expressed in cancer

2006-09-12

2006-09-12

Spector, Lorraine (Department: 1647)

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

C435S252300, C435S320100, C435S325000, C530S350000, C536S023100, C536S023500

Reexamination Certificate

active

07105315

ABSTRACT:
The invention provides a transmembrane protein that is differentially expressed in neoplastic disorders. It also provides for the use of the protein, a cDNA encoding the protein, and antibodies that specifically bind the protein in various methods to diagnose, stage, treat, or monitor the treatment of a neoplastic disorder.

REFERENCES:
GenBank Accession No. AI304327, Feb. 1, 1999.
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Chen et al. (2002). Discordant protein and mRNA expression in lung adenocarcinomas. Molecular and Cellular Proteomics. 1:304-313.
GenBank Accession No. AI281211, Jan. 28, 1999.
Cohen et al. “Cancer: Principles and Practices of Oncology”, In: DeVita, Lippincott, Williams & Wilkins, pp. 1148-1149 (2001).
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Bradley et al. “Increased expression of the epidermal growth factor receptor on human colon carcinoma cells”Arch Sug, Nov. 1986 ABSTRACT.
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