Transmembrane delivery peptide and bio-material comprising...

Details Transmembrane delivery peptide and bio-material comprising... Transmembrane delivery peptide and bio-material comprising...

2011-08-09

2011-08-09

Li, Q. Janice (Department: 1633)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

C424S093200, C424S093210, C435S325000, C530S300000, C536S023100

Reexamination Certificate

active

07994148

ABSTRACT:
The present invention relates to a transmembrane delivery peptide derived from human in which a target protein may be easily delivered into cells, and a recombinant vector comprising a nucleic acid coding the peptide. More specifically, the present invention relates to the transmembrane delivery peptide having an amino acid sequence described in SEQ ID No. 1 including 11 amino acids of specific sites in amino acid sequences of human G protein alpha 12, and a recombinant vector comprising a nucleic acid coding the same, a transformant prepared by introducing said recombinant vector, and the like. Since transmembrane delivery peptides of the present invention can be efficiently delivered into cells, they may be usefully used for the purposes of delivering various target materials, including proteins, nucleic acid, drugs and the like.

REFERENCES:
patent: 5652122 (1997-07-01), Frankel et al.
patent: 5998206 (1999-12-01), Cowsert
patent: 10-2005-0029879 (2005-03-01), None
International Search Report and Written Opinion dated Nov. 8, 2007, in Application No. PCT/KR2007/003734.
Iida, A. et al., “Identification of 20 nevel SNPs in the guanine nucleotide binding protein alpha 12 gene locus.” J. Hum. Genet. vol. 49(8) pp. 445-448, Jun. 18, 2004.

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