Translation inhibiting peptide

Details Translation inhibiting peptide Translation inhibiting peptide

1987-08-05

1989-09-19

Phillips, Delbert R.

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

530300, 530324, 530325, 530326, C07K 1500, C07K 708, C07K 710

Patent

active

048682861

ABSTRACT:
A peptide that causes a suppression in protein synthesis by halting the translation of mRNA into protein, the peptide having a Stokes radius of less than 16 Angstroms, a molecular weight, determined by SDS-PAGE, of 17 kD (indicating that the peptide is a monomer) and an isoelectric point of 7.25. The peptide of the present invention may have therapeutic advantages in halting the proliferation of abnormal or excess protein,

REFERENCES:
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