Transition state analogs

Details Transition state analogs Transition state analogs

1994-11-02

1999-09-14

Achutamurthy, Ponnathapura

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

Cyclic peptides

530323, 530328, 530329, 530330, 530331, 530332, 530345, 530403, 540460, 540487, 540522, 544224, 548111, 556 19, 556406, 558 44, 558 48, C07K 512, A61K 3812

Patent

active

059524626

ABSTRACT:
Antigens capable of eliciting antibodies which can catalyze chemical reactions, in particular, the cleavage or formation of a peptide linkage, comprising a hapten or a hapten and a suitable carrier molecule are disclosed. Haptens include, among others, silicon and boron containing compounds. Antibodies which are catalytically active for chemical reactions, in particular, the cleavage or formation of a selected peptide linkage or an ester bond, and which are elicited by such antigens are disclosed as well as methods for producing the antibodies and methods for catalyzing the cleavage or formation of a peptide linkage or in ester bond in a molecule.

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