Transhybridomas

Details Transhybridomas Transhybridomas

1990-02-27

1991-12-17

Weimar, Elizabeth C.

Chemistry: molecular biology and microbiology

Spore forming or isolating process

43524026, 435 694, 4351722, 4351723, 800 2, 800DIG1, 935 70, 935103, C12N 500, C12N 1500

Patent

active

050734903

ABSTRACT:
Tissue cell culture preparations derived from the cells of a transgenic animal are disclosed. These tissue cell preparations are capable of expressing a non-analogous gene product, i.e., a gene product which is not naturally produced by the animal cells.
Transhybridomas, i.e., hybridomas and immortalized cells created using cells obtained from transgenic animals, and methods for creating these transhybridomas are also disclosed. In particular, two transhybridomas, A 15.9 and B 6.4, both capable of producing human growth hormone, have been disclosed.

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Ornitz et al., Nature 313: 600-602 (1985).
Lichtman et al., Nature 324: 489-491 (1986).

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