Transglutaminase and gene encoding same

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

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435 691, 435 9121, 4353201, 536 2433, C12Q 168

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active

061141194

ABSTRACT:
A pair of degenerate oligonucleotide primers can amplify transglutaminase-specific fragments of known transglutaminase genes. The primers are also used to obtain new transglutaminase gene products. The nucleotide sequence of a novel transglutaminase gene (termed TG.sub.X) is presented.

REFERENCES:
patent: 5514579 (1996-05-01), O'Hara et al.
patent: 5549904 (1996-08-01), Juergensen et al.
Aeschlimann et al. Thrombosis and Haemostasis. vol. 71, No. 4, pp. 402-415, 1994.
Ichinose et al. PNAS. vol. 85, pp. 5829-5833, 1988.
Aeschlimann, Daniel, et al., "Transglutaminases: Protein Cross-Linking Enzymes in Tissues and Body Fluids," Thrombosis and Haemostasis, 71(4):402-415 (1994).

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