Transgenic rats and spermatogonial stem cells

Multicellular living organisms and unmodified parts thereof and – Nonhuman animal – Transgenic nonhuman animal

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C435S325000, C435S455000

Reexamination Certificate

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07491866

ABSTRACT:
A transgenic rat expresses a gene of interest, such as EGFP, exclusively in the germ cells of both males and females. From such a transgenic rat one can isolate a line of spermatogonial stem cells, which can renew and proliferate in culture.

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