Transgenic pathogen-resistant organism

Drug – bio-affecting and body treating compositions – Enzyme or coenzyme containing – Hydrolases

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424 942, 514 12, 435200, 435209, A61K 3854, A61K 3847, A61K 3816

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active

058041842

ABSTRACT:
Transgenic pathogen-resistant organism whose genome contains at least two different genes under the control of active promoters with pathogen-inhibiting action. This organism is distinguished by a synergistic pathogen-inhibiting action. This action is evident particularly when the genes code for the gene products chitinase (ChiS, ChiG), glucanase (GluG), protein synthesis inhibitor (PSI) and antifungal protein (AFP).

REFERENCES:
patent: 4940840 (1990-07-01), Suslow et al.
R. Leah et al., "Biochemical and Molecular Characterization of Three Barley eed Proteins With Antifungal Properties", J. Biol. Chem. 266(3): 1564-1573, Jan. 1991.
S. Wnendt et al., "Cloning and Nucleotide Sequences of a cDNA Encoding the Antifungal-Protein of Aspergillus giganteus and Preliminary Characterization of the Native Gene", Nuc. Acid Res. 18(13): 3987, Jul. 1990.

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