Transgenic non-human mammal

Details Transgenic non-human mammal Transgenic non-human mammal

2004-10-28

2009-06-23

Wilson, Michael C. (Department: 1632)

Multicellular living organisms and unmodified parts thereof and

Nonhuman animal

Transgenic nonhuman animal

C800S008000

Reexamination Certificate

active

07550649

ABSTRACT:
An object of the present invention is to provide a model animal of Parkinson's disease comprising an α-synuclein gene introduced therein. The present invention provides a transgenic non-human mammal or a portion thereof, wherein an α-synuclein gene is introduced and the gene is expressed in neurons, and the number of dopamine-producing neurons in the substantial nigra is significantly decreased as compared with that of a wild-type animal.

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