Drug – bio-affecting and body treating compositions – In vivo diagnosis or in vivo testing – Testing efficacy or toxicity of a compound or composition
Patent
1995-06-07
1998-01-20
Crouch, Deborah
Drug, bio-affecting and body treating compositions
In vivo diagnosis or in vivo testing
Testing efficacy or toxicity of a compound or composition
800 2, 800DIG1, A61K 4900, C12N 500, C12N 1500
Patent
active
057098441
ABSTRACT:
The present invention relates to improved models for progressive epithelial neoplasias and methods for their use. In particular, the invention provides transgenic mice comprising a human papilloma virus early region oncogene operably linked to a promoter which directs expression of the oncogene in a transient amplifying cell in the mice.
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Arbeit Jeffrey M.
Hanahan Douglas
Crouch Deborah
The Regents of the University of California
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