Multicellular living organisms and unmodified parts thereof and – Nonhuman animal
Patent
1994-06-09
1997-12-16
Crouch, Deborah
Multicellular living organisms and unmodified parts thereof and
Nonhuman animal
800DIG1, 424 92, C12N 500, C12N 1500, A61K 4900
Patent
active
056987641
ABSTRACT:
The present invention relates to improved models for progressive epithelial neoplasias and methods for their use. In particular, the invention provides transgenic mice comprising a human papilloma virus early region oncogene operably linked to a promoter which directs expression of the oncogene in a transient amplifying cell in the mice.
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Arbeit Jeffrey M.
Hanahan Douglas
Howley Peter M.
Crouch Deborah
The Regents of the University of California
The United States of America as represented by the Secretary of
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