Transgenic mice expressing a mutated human collagen gene

Details Transgenic mice expressing a mutated human collagen gene Transgenic mice expressing a mutated human collagen gene

1994-03-16

1997-09-02

Crouch, Deborah

Multicellular living organisms and unmodified parts thereof and

Nonhuman animal

800DIG1, 424 91, C12N 500, C12N 1500, A61K 4900

Patent

active

056634820

ABSTRACT:
The invention is transgenic mice substantially all of whose cells contain a mutated human collagen gene. Methods for testing therapies for the treatment of osteogenesis imperfecta, osteoporosis, and chondrodysplasia are provided.

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