Multicellular living organisms and unmodified parts thereof and – Nonhuman animal
Patent
1995-04-25
1998-12-15
Chambers, Jasemine C.
Multicellular living organisms and unmodified parts thereof and
Nonhuman animal
435 697, 435 691, 4351723, 435 912, 424 92, 536 231, 536 234, 536 235, 536 241, C12N 500, C12N 1500, C12N 1509
Patent
active
058499938
ABSTRACT:
Transgenic mice carrying a recombinant DNA construct comprising the gene encoding diphtheria toxin A chain operably linked to a osteocalcin promoter. The transgenic mice can be used as a model for metabolic bone diseases since they have decreased bone mass associated with a marked reduction in the number of osteoblasts.
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Hirokawa Katsuiku
Ikeda Toru
Kobayashi Takashi
Sato Masahiro
Tada Norihiro
Chambers Jasemine C.
Hoechst Japan Limited
Schmuck Jill D.
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