Multicellular living organisms and unmodified parts thereof and – Method of introducing a polynucleotide molecule into or... – Nonplant protein is expressed from the polynucleotide
Reexamination Certificate
2006-07-25
2006-07-25
McElwain, Elizabeth (Department: 1638)
Multicellular living organisms and unmodified parts thereof and
Method of introducing a polynucleotide molecule into or...
Nonplant protein is expressed from the polynucleotide
C800S292000, C800S293000, C800S300000, C800S295000, C435S320100, C435S419000, C435S468000, C435S470000, C536S023100
Reexamination Certificate
active
07081567
ABSTRACT:
Disclosed is a method for making a bioreactor comprising a foreign target gene, special selectable markers and Dunaliella Salina as host. It is prepared by the genetic transformation techniques that include introducing a foreign target gene into the cells of Dunaliella Salina and screening the transformed cells of Dunaliella Salina. The bioreactor of the present invention can be used as a safe and cheap production system for proteins of pharmaceutical interest including vaccines, especially oral products, in a large scale, because the cells of Dunaliella Salina are easy of genetic manipulation in preparation of the bioreactor, nontoxic and edible for humans and animals, and harmless to the environment.
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Jiang Guozhong
Pan Weidong
Wang Jianmin
Xue Lexun
McElwain Elizabeth
Morgan & Finnegan , LLP
Xue Lexun
Zhengzhou University
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