Transgenic,cross-linked hemoglobin

Details Transgenic,cross-linked hemoglobin Transgenic,cross-linked hemoglobin

1997-03-11

1998-12-15

Carlson, Karen C.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

530385, C07K 14805

Patent

active

058496882

ABSTRACT:
Transgenic, recombinantly cross-linked polymeric human hemoglobins suitable as cell-free blood substitutes have been produced. A plurality of DNA constructs have been designed for efficient expression of modified human hemoglobins in the erythrocytes of the non-human transgenic animals. Substantially pure, non-immunogenic, artificial human hemoglobins are then easily obtained from the erythroid cells of the transgenic animals.

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