Multicellular living organisms and unmodified parts thereof and – Nonhuman animal
Patent
1996-06-06
1998-08-04
Chambers, Jasemine C.
Multicellular living organisms and unmodified parts thereof and
Nonhuman animal
4351723, 424 91, 424 92, C12N 1500, A61K 4900
Patent
active
057896550
ABSTRACT:
DNA constructs are provided of epitope-tagged proteins or protein fragments which are conveniently purified with immunoaffinity chromatography such as epitope-tagged prion proteins (PrP). Transgenic animals expressing an epitope-tagged protein are provided, including transgenic animals expressing epitope-tagged PrP. Methods for distinguishing between the conformational shapes of a protein and a convenient method for isolating a tagged protein by immunoaffinity chromatographic methods are provided.
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Cohen Fred E.
Prusiner Stanley B.
Scott Michael R.
Telling Glenn C.
Bozicevic, Esq. Karl
Chambers Jasemine C.
Clark Deborah J. R.
The Regents of the University of California
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