Multicellular living organisms and unmodified parts thereof and – Nonhuman animal
Patent
1992-09-23
1997-02-11
Stone, Jacqueline M.
Multicellular living organisms and unmodified parts thereof and
Nonhuman animal
800DIG1, 4351723, 4353201, 536 235, A01K 6700, C12N 1500
Patent
active
056022999
ABSTRACT:
The design, construction, and use of transgenic animals which exhibit features, including neurofibrillary tangles and aluminum sensitivity, is described. The founder transgenic animals of the invention are produced by methods well known in the art, and utilize DNA sequences designed to express all or any part of the human neurofilament subunit genes, NF-L, NF-M, NF-H, in a neural-enriched manner.
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Campbell Bruce
Mount Sinai School of Medicine of the City University of New Yor
Stone Jacqueline M.
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