Transgenic animal containing CD200 and uses therefor

Details Transgenic animal containing CD200 and uses therefor Transgenic animal containing CD200 and uses therefor

2007-03-27

2007-03-27

Kaushal, Sumesh (Department: 1633)

Multicellular living organisms and unmodified parts thereof and

Nonhuman animal

Transgenic nonhuman animal

C800S003000, C800S008000, C800S014000, C800S021000, C800S024000, C800S025000, C435S069100, C435S320100, C435S325000, C435S455000

Reexamination Certificate

active

10406004

ABSTRACT:
The present invention is directed toward a transgenic non-human animal and uses thereof, wherein each of the cells of the animal contain a transgene comprising a nucleic acid sequence encoding CD200.

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Holschneider et al. Int J. Devl. Neuroscience 18:615-618, 2001.
Hoek et al., Down-Regulation of the Macrophage Lineage Through Interaction with OX2 (CD200), Science, vol. 290, pp. 1768-1771, 2000.

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