Transgenic animal allergy models and methods for their use

Details Transgenic animal allergy models and methods for their use Transgenic animal allergy models and methods for their use

1998-11-13

2000-09-12

LeGuyader, John

Multicellular living organisms and unmodified parts thereof and

Method of using a transgenic nonhuman animal in an in vivo...

800 6, 800 8, 800 21, 800 25, 435 6, 435 696, 4353201, 435376, A01K 6702, C12Q 168, C12N 1585

Patent

active

061180440

ABSTRACT:
Transgenic mice which constitutively express an antibody-type molecule encoded by the transgene and which has an IgE heavy chain constant region and is specific for a pre-defined antigen, provide an allergic reaction to that antigen without prior sensitization and are useful as allergy models.

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