Transformed cell with enhanced sensitivity to antifungal...

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving transferase

Reexamination Certificate

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C435S252300, C536S023200

Reexamination Certificate

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07964373

ABSTRACT:
The present invention provides a transformed cell in which a polynucleotide having a nucleotide sequence encoding an amino acid sequence of an osmosensing histidine kinase having no transmembrane region is introduced in a functional form into a cell deficient in at least one hybrid-sensor kinase, a method of assaying the antifungal activity of a test substance using the transformed cell, and a method of searching an antifungal compound using the method, and the like.

REFERENCES:
patent: 5939306 (1999-08-01), Alex et al.
patent: WO 98/44148 (1998-10-01), None
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