Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Patent
1998-07-28
2000-03-28
Trinh, Ba K.
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
549511, C07D30514
Patent
active
060433825
ABSTRACT:
A method for esterifying C13 deoxy taxoid intermediates employs three steps, i.e., oxygenation of the C13 deoxy taxoid intermediate to produce a C13 enone taxoid intermediate; reduction of the C13 enone to produce an alcohol; followed by esterification of the C13 alcohol. Key intermediates include C13 deoxy taxoids; C13 enone substituted taxoids; and C1-C2 cyclo carbonate esters of taxoids.
REFERENCES:
patent: 5440057 (1995-08-01), Nicolaou et al.
patent: 5504222 (1996-04-01), Nicolaou et al.
Guy Rodney K.
Nantermet Philippe G.
Nicolaou K.C.
Ueno Hiroaki
Lewis Donald G.
The Scripps Research Institute
Trinh Ba K.
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