Chemistry: analytical and immunological testing – Peptide – protein or amino acid – Glycoproteins
Reexamination Certificate
2007-01-23
2007-01-23
Cole, Monique T. (Department: 1743)
Chemistry: analytical and immunological testing
Peptide, protein or amino acid
Glycoproteins
C436S808000, C436S811000, C210S634000, C210S644000, C210S645000
Reexamination Certificate
active
10167983
ABSTRACT:
The invention relates to an assay method for assessing a transferrin variant or combination of transferrin variants for the diagnosis and monitoring of alcoholism, and to kits for performing the assay. In particular, the invention provides a method of producing an algorithm for determining the content of a transferrin variant or combination of transferrin variants, preferably a CDT variant or combination of CDT variants, in a sample of body fluid, said method comprising: (a) obtaining at least two solutions each having known contents of asialo- (A1, A2, A3, etc.) and disialo-transferrins (D1, D2, D3, etc.); (b) determining the content in each of said solutions of a transferrin variant or combination of transferrin variants fractions substantially free from tri- and higher sialylated transferring; (c) determining the total transferrin variant content (T1, T2, T2, etc.) of said fractions; and (d) producing an algorithm capable of determining the content of any transferrin variant or combination of transferrin variants, preferably a CDT variant or combination of CDT variants, in any given sample of body fluid subjected to said determination step b).
REFERENCES:
patent: 4626355 (1986-12-01), Joustra et al.
patent: 5352616 (1994-10-01), Sundrehagen
patent: 5788845 (1998-08-01), Jeppsson
patent: 5798212 (1998-08-01), Sundrehagen
patent: 6103478 (2000-08-01), Sundrehagen
patent: 6716641 (2004-04-01), Sundrehagen
patent: WO-96/26444 (1996-08-01), None
patent: WO-99/00672 (1999-01-01), None
Eilertsen Ingar
Husa Asgeir
Sundrehagen Erling
Axis-Shield ASA
Cole Monique T.
Schwegman Lundberg Woessner & Kluth P.A.
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