Chemistry: molecular biology and microbiology – Process of mutation – cell fusion – or genetic modification – Introduction of a polynucleotide molecule into or...
Reexamination Certificate
2002-06-20
2009-06-16
Ketter, James S (Department: 1636)
Chemistry: molecular biology and microbiology
Process of mutation, cell fusion, or genetic modification
Introduction of a polynucleotide molecule into or...
C435S366000, C435S372000
Reexamination Certificate
active
07547551
ABSTRACT:
The present invention provides an improved method for gene delivery in eukaryotic cells by electroporation, preferably in human hematopoietic cells, particular dendritic cells. The method of the invention is superior to lipofection and passive pulsing of mRNA and to electroporation of plasmid cDNA for gene delivery, including tumor antigen loading of dendritic cells.
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Berneman Zwi N.
Ponsaerts Peter
Schuler Gerold
Strobel Isolde
Van Tendeloo Viggo F. I.
Ketter James S
Norris McLaughlin & Marcus PA
Schuler Gerold
Strobel Isolde
University of Antwerp.
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