Transduced mesenchymal stem cells

Details Transduced mesenchymal stem cells Transduced mesenchymal stem cells

1993-11-24

1997-01-07

Fleisher, Mindy

Chemistry: molecular biology and microbiology

Spore forming or isolating process

424 937, 424 9321, 4351723, 4353201, 935 62, 935 70, 935 71, C12N 510, C12N 508, C12N 1586, A61K 4800

Patent

active

055916252

ABSTRACT:
Genetically engineered human stem cells that carry within them genes of interest particularly for the expression of physiologically or pharmacologically active proteins or for use in gene therapy. In addition to correction of genetic disorders, is the ability to introduce, in a targeted manner, additional copies of essential genes to allow expression in proliferating, nondifferentiating cells of certain gene products. These genes can be, for example, hormones matrix proteins, cytokines, adhesion molecules, detoxification enzymes and "rebuilding" proteins important in tissue repair.

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