Transduced fibroblasts

Chemistry: molecular biology and microbiology – Treatment of micro-organisms or enzymes with electrical or... – Modification of viruses

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424 9321, 435 691, 4352401, 4352402, 43524023, 43524024, 4353201, 935 32, 935 34, 935 57, 935 62, 935 70, 935 71, C12N 510, C12N 1586

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054609593

ABSTRACT:
Fibroblasts transduced with genetic material encoding a polypeptide or protein of interest and, optionally, a selectable marker, as well as methods for making and using the transduced fibroblasts. Such fibroblasts are useful in delivering the encoded polypeptide or protein, such as an enzyme, a hormone or a drug, to an individual who has had a graft or implant of the transduced cells.

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