Transdiffentiation of transfected epidermal basal cells into...

Chemistry: molecular biology and microbiology – Process of mutation – cell fusion – or genetic modification – Introduction of a polynucleotide molecule into or...

Reexamination Certificate

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C435S325000, C435S006120, C435S366000, C435S375000, C536S023100, C536S024500

Reexamination Certificate

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07041507

ABSTRACT:
Disclosed is an in vitro method of transdifferentiating an epidermal basal cell into a cell having one or more morphological, physiological and/or immunological features of a glial cell. Also disclosed are such transdifferentiated cells and cell cultures derived from them. A kit for converting, in vitro, epidermal basal cells into cells having one or more morphological, physiological and/or immunological features of a glial cell is also disclosed.

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