Transdermal treatment for pain and inflammation with 2-amino-3-a

Details Transdermal treatment for pain and inflammation with 2-amino-3-a Transdermal treatment for pain and inflammation with 2-amino-3-a

1985-10-28

1987-07-28

Friedman, Stanley J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Ester doai

514562, A61K 3124, A61K 31195

Patent

active

046832424

ABSTRACT:
A method is disclosed for treating pain and/or inflammation by transdermal administration of 2-amino-3-benzoylbenzeneacetic acids, salts and esters having the formula ##STR1## wherein R.sup.1 is hydrogen, loweralkyl or a pharmaceutically acceptable cation; R.sup.2 is hydrogen, halogen, loweralkyl or loweralkoxy; R.sup.3, R.sup.4 and R.sup.5 are hydrogen or loweralkyl; X is hydrogen, halogen, loweralkyl, hydroxy, loweralkoxy, nitro, trifluoromethyl or loweralkylthio; Y is hydrogen, loweralkyl, loweralkoxy, nitro or trifluoromethyl and hydrates and alcoholates thereof.

REFERENCES:
patent: 4045576 (1977-08-01), Welstead et al.
patent: 4503073 (1985-05-01), Walsh et al.

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