Transdermal transport using ultrasonic standing waves

Details Transdermal transport using ultrasonic standing waves Transdermal transport using ultrasonic standing waves

1996-02-23

1999-04-20

Apley, Richard J.

Surgery

Diagnostic testing

Liquid collection

600584, A61B 500, B65D 8100

Patent

active

058953620

ABSTRACT:
A process for the sampling of extracellular fluid across the skin of an animal involves establishing an ultrasonic standing wave across the skin and collecting fluid transudate. Sampling can be enhanced by combining the use of ultrasound with the application of a partial vacuum to the surface of the skin. An apparatus includes an ultrasonic transducer, a reflector and an absorbent material for collecting transudate. The apparatus can further include a pressure component for reducing hydrostatic pressure on the skin surface.

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