Transdermal thermal polymerization

Details Transdermal thermal polymerization Transdermal thermal polymerization

2006-08-29

2006-08-29

Webman, Edward J. (Department: 1616)

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Matrices

C424S487000, C424S422000, C424S423000, C424S424000, C424S425000, C424S426000, C424S428000, C514S944000

Reexamination Certificate

active

07097855

ABSTRACT:
An invention for polymerizing or crosslinking a prepolymer using a water soluble, thermal polymerization initiator is disclosed. The prepolymer mixed with the initiator is injected or placed into an animal's body, and heat is applied over the site of the injection to polymerize the polymer. This transdermal thermal polymerization system can be used for drug delivery of bioactive agents in tissue engineering applications in which living cells are delivered.

REFERENCES:
patent: 3997497 (1976-12-01), Itoh et al.
patent: 4379864 (1983-04-01), Gallop et al.
patent: 4622371 (1986-11-01), McDaniel
patent: 4638040 (1987-01-01), Hammar
patent: 4789547 (1988-12-01), Song et al.
patent: 4938763 (1990-07-01), Dunn et al.
patent: 5278201 (1994-01-01), Dunn et al.
patent: 5278202 (1994-01-01), Dunn et al.
patent: 5340849 (1994-08-01), Dunn et al.
patent: 5410016 (1995-04-01), Hubbell et al.
patent: 5618800 (1997-04-01), Kabra et al.
patent: 5626863 (1997-05-01), Hubbell et al.
patent: 5702717 (1997-12-01), Cha et al.
patent: 5733950 (1998-03-01), Dunn et al.
patent: 5736152 (1998-04-01), Dunn
patent: 5739176 (1998-04-01), Dunn et al.
patent: 5741542 (1998-04-01), Williams et al.
patent: 5744153 (1998-04-01), Yewey et al.
patent: 5759563 (1998-06-01), Yewey et al.
patent: 5834274 (1998-11-01), Hubbell et al.
patent: 5843743 (1998-12-01), Hubbell et al.
patent: 5858746 (1999-01-01), Hubbell et al.
patent: 33 12 424 (1984-10-01), None
patent: WO 94/25080 (1994-11-01), None
The International Search Report.
Hill-West et al., “Prevention of Postoperative Adhesions in the Rat by Situ Photopolymerization of Bioresorbable Hydrogel Barriers”, Obstetrics & Gynecology, 83(1): 59-64, 1994.
Kathmann et al., “Water-Soluble Copolymers, 67. Polyelectrolytes of N-Vinylformamide with Sodium 3-Acrylamido-3-Methylbutanoate, Sodium 2-Acrylamido-2-Methylpropanesulfonate, and Sodium Acrylate: Synthesis and Characterization”,Macromolecules, 29: 5268-5272, 1996.
U.S. Appl. No. 08/862,740, Langer et al.
Elisseeff, et al., “Transdermal Photopolymerization for Minimally Invasive Implantation”Proc. Natl. Acad. Sci. USA96(6):3104-3107, 1999.
Langer, R. “1994 Whitaker Lecture: Polymers for Drug Delivery and Tissue Engineering”Ann. Biomed Eng.23(2):101-111, 1995.
Peter, et al., “Polymer Concepts in Tissue Engineering”J. Biomed. Mater. Res.43(4):422-427, 1998.
Potts, et al., “Transdermal Drug Delivery: Useful Paradigms”J. Drug Target3(4):247-251, 1995.
Sims, et al., “Injectable Cartilage Using Polyethylene Oxide Polymer Substrates”Plastic Reconstructive Surgery98:843-850, 1996.
Technical Information on VA-044, Wako Pure Chemical Industries, Ltd., Japan, 1-8.
Technical Information on VA-50, Wako Pure Chemical Industries, Ltd., Japan, 1-21.

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