Transdermal therapeutic system for treating Parkinsonism

Details Transdermal therapeutic system for treating Parkinsonism Transdermal therapeutic system for treating Parkinsonism

2007-10-31

2008-08-19

Ghali, Isis A (Department: 1611)

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Web, sheet or filament bases; compositions of bandages; or...

C424S449000, C424S443000, C424S484000, C424S485000, C424S486000

Reexamination Certificate

active

07413747

ABSTRACT:
A transdermal therapeutic system (TTS) comprises a silicone-based polymer adhesive system having distributed therein (−)-5,6,7,8-tetrahydro-6-[propyl-[2-(2-thienyl)ethyl]amino]-1-naphthalenol free base in an amount of about 5% to 40% by weight. The adhesive system comprises a silicone adhesive and an additive having increased solubility for the active substance, in an amount effective to increase dissolving capacity of the matrix for the active substance.

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Timmerman, W. et al. (1989) European Journal of Pharmacology 162:143-150.

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