Transdermal therapeutic system exhibiting an increased active su

Details Transdermal therapeutic system exhibiting an increased active su Transdermal therapeutic system exhibiting an increased active su

1990-03-28

1993-07-27

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Web, sheet or filament bases; compositions of bandages; or...

424443, 424445, 424484, 424486, A61K 970, A61K 914, A61K 4736, A61L 1542

Patent

active

052308987

ABSTRACT:
A transdermal therapeutic system exhibiting layered structure consists of a backing layer which is impermeable to active substances, a matrix having water-insoluble basic material and islands (inclusions) divided therein, and a layer controlling the access of cutaneous liquid by means of which the matrix is activatable. Process for the production are described.

REFERENCES:
patent: 3921636 (1975-11-01), Zaffaroni
patent: 3993072 (1976-11-01), Zaffaroni
patent: 4314557 (1982-02-01), Chandrasekaran
patent: 4781924 (1988-11-01), Lee et al.
patent: 4834978 (1989-05-01), Nuwayser
patent: 4837027 (1989-06-01), Lee et al.
patent: 4942037 (1990-07-01), Bondi et al.
Yie W. Chien, "Development of Transdermal Drug Delivery Systems," in Drug Development and Industrial Pharmacy, 1987, pp. 589-651.

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