Transdermal therapeutic system comprising the active subtance 17

Details Transdermal therapeutic system comprising the active subtance 17 Transdermal therapeutic system comprising the active subtance 17

1997-05-09

1998-10-27

Weiss, John G.

Surgery

Means for introducing or removing material from body for...

Treating material applied to or removed from external...

424449, A61F 1302, A61K 916

Patent

active

058272453

ABSTRACT:
A transdermal therapeutic system containing the active substance 17-.beta.-estradiol and optionally further active substances has a laminated structure positioned on a backing layer which is essentially impermeable to active substance and moisture, at least one matrix layer and optionally an adhesive layer. The at least one matrix layer or the adhesive layer contains anhydrous 17-.beta.-estradiol in crystalline form.

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Busetta et Michel Hospital "Structure Cristalline . . ." Acta Cryst. 1972, B28, pp. 560-567.
Kuhnert-Brandstatter and H. Winkler (1976) Scientia Pharmaceutica 44 (3) pp. 177-190.

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