Transdermal patch for comparative evaluations

Details Transdermal patch for comparative evaluations Transdermal patch for comparative evaluations

1996-01-05

1998-03-31

Phelan, D. Gabrielle

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Web, sheet or filament bases; compositions of bandages; or...

424448, A61F 1300

Patent

active

057335710

ABSTRACT:
A transdermal patch useful for evaluating the therapeutic effectiveness of a transdermally delivered medicinal agent is disclosed. The patch includes a substantially impermeable backing layer, a delivery layer containing a medicament and a substantially impermeable blocking layer. The delivery layer is arranged between the backing and blocking layers to prevent the release of the medicament contents from the delivery layer when the transdermal patch is affixed to the skin of a mammal. In alternative embodiments, non-transdermal placebo systems such as oral dosage forms which are coated with substantially impermeable layers to create virtually identical placebos of active oral delivery systems such as tablets, capsules and osmotic tablets are disclosed. Methods of comparing the therapeutic effectiveness of active dosage forms, i.e. transdermal units containing a medicament to placebo or to comparable active agents in either similar or different delivery systems are also disclosed.

REFERENCES:
patent: 4379454 (1983-04-01), Campbell et al.
patent: 4806341 (1989-02-01), Chien et al.
patent: 4846826 (1989-07-01), Shaw
patent: 4983395 (1991-01-01), Chang et al.
patent: 5069909 (1991-12-01), Sharma et al.
patent: 5240711 (1993-08-01), Hille et al.
patent: 5273755 (1993-12-01), Venkatrama
Duragesic .TM. (fentanyl transdermal system), Physician's Desk Reference, 47th Edition, 1993, pp. 1160-1164.

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