Transdermal nitroglycerin delivery system

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Web – sheet or filament bases; compositions of bandages; or...

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424 78, 424 81, 424448, 514509, 604896, 604897, A61F 1300, A61K 970

Patent

active

047510870

ABSTRACT:
A pressure-sensitive adhesive tape for delivering nitroglycerin to skin, the tape comprising a backing with a layer of inert pressure-sensitive adhesive attached thereto, said pressure-sensitive adhesive layer comprising a pressure-sensitive adhesive polymer, skin penetration-enhancing ingredients and a relatively high concentration of nitroglycerin. The tape is useful for systemic treatment of angina pectoris, control of hypertension and treatment of congestive heart failure.

REFERENCES:
patent: 3742951 (1973-07-01), Zaffaroni
patent: 4409206 (1983-10-01), Stricker
patent: 4485087 (1984-11-01), Otsuka et al.
patent: 4542013 (1985-09-01), Keith
patent: 4585452 (1986-04-01), Sablotsky
patent: 4588580 (1986-05-01), Gale et al.
Japanese application 57-58617, together with non-certified English translation.
Patent Abstract of Japan, vol. 9, No. 66 (C-271)[1789]3/26/85.
Chem. Abstract, vol. 98, No. 16 (Apr. 18, 1983).
EPO Laid-Open Application 062682 Nippon Kayaku Kabushiki Kaisha.

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