Transdermal hormone patch

Details Transdermal hormone patch Transdermal hormone patch

1998-01-22

1999-11-16

Brouillette, D. Gabrielle

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Implant or insert

514946, 514947, A61F 1302

Patent

active

059853115

ABSTRACT:
A transdermal therapeutic system (TTS) which contains as the active ingredients an oestrogen and a gestagen or a gestagen or androgen as well as an acrylate adhesive and, as resorption promoters, the two substances oleic acid and 2-(2-ethoxyethoxy)ethanol.

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Franz, "Percutaneous Absorption on the Relevance of In Vitro Data", The Jnal of Investigate Dermatology, 64:190-195 (1975).
Katz et al., "Enhanced skin Permeation of Prazosin by Transcutol-Oleic Acid Mixture", Proceed. Intern. Symp. Control. Rel. of Bioact. Mater., 18: 533-534 (1991).
Frieg-Falson et al., "Characterization of the Enhancing Effect of a Vehicle in a Transdermal System", Drug Development and Industrial Pharmacy, 15(14-16), 2393-2406 (1989).
Watkinson et al., "Aspects of the Transdermal Delivery of Prostaglandins", International Journal of Pharmaceutics, 74 (1991) 229-256.
Walters et al., "Penetration Enhancers and Their Use in Transdermal Therapeutic Systems", Transdermal Drug Delivery: Developmental Issues and Research Initiatives, edited by Hadgraft and Guy, Marcel Dekker, Inc., 1989, pp.
Abstract of Katz et al., "Enhanced Skin Permeation of Prazosin by Transutol-oleic Acid Mixture", Proc. Program. Int. Symp. Controlled Release Bioact. Mater., 18.sup.th (1991) 533-544.
Abstract of Rieg-Falson et al., "Evaluation of a Transdermal Device Containing Testosterone", Bull. Tech./Gattefosse Rep., 78: 89-96 (1985).
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