Transdermal flux enhancers in combination with iontophoresis in

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Web – sheet or filament bases; compositions of bandages; or...

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514946, 514947, 604 20, A61F 1300

Patent

active

050230859

ABSTRACT:
Transdermal flux enhancers such as oleic acid and 1-dodecylazacycloheptan-2-one are used in combination with iontophoresis in the topical administration of pharmaceutical agents.

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Cooper, Eugene R., J. Pharm. Sci., 73, 1153 (1984).
Tyle, Praveen, Pharm. Res. 3, 318 (1986).
Burnette, R. R. et al., J. Pharm. Sci., 75, 738 (1986).
Meyer, B. Robert et al., Am. J. Med. Sci., 297, 321 (1989).
Stoughton, Richard B., Arch. Derm. 118, 474 (1982).

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