Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Web – sheet or filament bases; compositions of bandages; or...
Patent
1988-01-26
1989-09-19
Griffin, Ronald W.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Web, sheet or filament bases; compositions of bandages; or...
424DIG14, 424447, A61K 970, A61K 13405, A61L 1503
Patent
active
048679828
ABSTRACT:
A medical device for the transdermal delivery of an active agent through sensitive intact skin is provided. The device comprises a matrix containing the drug having reinforcing means, preferably in the form of a fabric, embedded in the upper surface of the matrix. The matrix is formed of an agent permeable material which is tacky but does not adhesively bond to the skin. The device is sufficiently flexible and deformable that the combination of tackiness, flexibility, and deformation permits the device to be maintained in agent transmitting relationship upon skin at such sensitive areas as the scrotum, labia, breast, or penis, for example. In certain embodiments, the skin distal surface is provided with a layer of an agent impermeable material to reduce transfer of the agent from the patient to others.
REFERENCES:
patent: 4379454 (1983-04-01), Campbell et al.
patent: 4704282 (1987-11-01), Campbell et al.
patent: 4725439 (1988-02-01), Campbell et al.
Campbell Patricia S.
Eckenhoff James B.
Place Virgil A.
ALZA Corporation
Griffin Ronald W.
Mandell Edward L.
Sabatine Paul L.
Stone Steven F.
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