Transdermal device for the delivery of testosterone

Details Transdermal device for the delivery of testosterone Transdermal device for the delivery of testosterone

1998-02-27

2000-10-17

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Web, sheet or filament bases; compositions of bandages; or...

424449, A61F 1302, A61F 1300

Patent

active

061327603

ABSTRACT:
A transdermal delivery device including an adhesive layer that contains a therapeutically effective amount of testosterone and a delivery enhancing adjuvant comprising a terpene.

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patent: 5679373 (1997-10-01), Wick
patent: 5866157 (1999-02-01), Higo
Misra et al "Biphasic Testosterone Delivery Profile Observed wth Two Different Transdermal Formulations" Pharmaceutical Research, 1997 vol. 14, No. 9, pp. No. 1264-1268.
Loftsson et al, "Cyclodextrins as Co-enhancers in Dermal and Transdermal Drug Delivery," Pharmazie, 1998, vol. 53 (2), pp. No. 137-139.
Article entitled The enhancement index concept applied to terpene penetration enhancers for human skin and model lipophilic (oestradiol) and hydrophilic (5-fluorouracil) drugs, by A.C. Williams and B.W. Barry, from the International Journal of Pharmaceutics, 74 (1991), pp. 157-168.

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