Transdermal delivery systems for the modulated administration of

Details Transdermal delivery systems for the modulated administration of Transdermal delivery systems for the modulated administration of

1995-06-06

1997-03-25

Weiss, John G.

Surgery

Means for introducing or removing material from body for...

Treating material applied to or removed from external...

6048901, 602 52, 602 54, 602 58, 424449, 514947, A61F 1302

Patent

active

056139586

ABSTRACT:
A transdermal delivery system for the modulated administration of drugs is described. The drug delivery device comprises a backing; a drug reservoir containing the drug, a plasticizer-type enhancer, a solvent-type enhancer, and optionally, a gelling agent; a non-rate-controlling membrane; and an adhesive layer containing a plasticizer-type enhancer. This drug delivery system is particularly useful for the administration of tolerance-inducing drugs, for example, vasodilators, such as isosorbide dinitrate.

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