Transdermal delivery system for alkaloids of aconitum species

Details Transdermal delivery system for alkaloids of aconitum species Transdermal delivery system for alkaloids of aconitum species

2005-05-24

2005-05-24

Coe, Susan (Department: 1654)

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Web, sheet or filament bases; compositions of bandages; or...

C424S400000, C514S279000

Reexamination Certificate

active

06896898

ABSTRACT:
The present invention provides a composition of transdermally administered aconitine alkaloids for ameliorating pain and inflammation. In one aspect, an aconitine alkaloid is delivered in a sufficient amount to achieve and maintain a blood plasma aconitine alkaloid level of about 0.5 ng/mL to about 400 ng/mL. Aconitine alkaloids may be delivered by themselves, or in combination with other elements, such as additional analgesics, other drugs, or positive health promoting substances. Various formulations for the transdermal delivery of aconitine alkaloids are disclosed, and may include selected penetration enhancers.

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