Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Reexamination Certificate
2006-09-14
2010-02-09
Gupta, Anish (Department: 1654)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
C530S327000, C530S328000
Reexamination Certificate
active
07659252
ABSTRACT:
Transdermal delivery peptides for the treatment of skin diseases and/or facilitation or enhancement of transdermal delivery of pharmaceutically active agents are provided. Compositions comprising the transdermal delivery peptides and methods of therapeutic use, including the improvement of transdermal delivery of drugs or other pharmaceutically active agents, are also disclosed. Nucleic acids, expression vectors, and methods of their use, which encode the transdermal delivery peptides are disclosed. Methods are also provided for in vivo phage display for identifying further peptides with enhanced transdermal delivery capability.
REFERENCES:
patent: 5534496 (1996-07-01), Lee et al.
patent: WO01/75067 (2001-10-01), None
Agarwal et al., 2000, “The Pilosebaceous Unit: A Pivotal Route for Topical Drug Delivery,” Methods Find. Exp. Clin. Pharmacol. 22:129.
Arap et al., 1998, “Cancer Treatment by Targeted Drug Delivery to Tumor Vasculature in a Mouse Model,” Science, 279:377.
BouHamdan et al., 1998, “Diversity of HIV-1 Vpr Interactions Involves Usage of the WXXF Motif of Host Cell Proteins,” J. Biol. Chem. 273:8009.
Duerr et al., 2004, “Identification of Peptide Sequences that Induce the Transport of Phage Across the Gastrointestinal Mucosal Barrier,” Journal of Virological Methods, 116:177-180.
Ferrer et al., 1999, “Structural and Functional Characterization of an Epitope in the Conserved C-Terminal Region of HIV-1 gp120,” J. Pept. Res.: 54, 32.
Finnin et al., 1999, “Transdermal Penetration Enhancers: Applications, Limitations, and Potential,” J. Pharm. Sci. 88:955.
Grams et al., 2002, “Penetration and Distribution of Three Lipophilic Probes in vitro in Human Skin Focusing on the Hair Follicle,” J. Controlled Release, 83:253.
Grams et al., 2004, “Time and Depth Resolved Visualisation of the Diffusion of a Lipophilic Dye into the Hair Follicle of Fresh Unfixed Human Scalp Skin,” J. Controlled Release, 98:367.
Hirvonen et al., 1996, “Transdermal Delivery of Peptides by Iontophoresis,” Nat. Biotechnol. 14:1710.
Hoffman, 1997, “Topical Liposome Targeting of Dyes, Melanins, Genes, and Proteins Selectively to Hair Follicles,” J. Drug Targeting, 5:67.
Joliot et al., 2004, “Transduction Peptides: From Technology to Physiology,” Nature Cell Biol., 16:189.
Kalia et al., 2004, “Iontophoretic Drug Delivery,” Adv. Drug Deliv. Rev. 56:619.
Kanikkannan et al., 2000, “Structure-Activity Relationship of a Chemical Penetration Enhancers in Transdermal Drug Delivery,” Curr. Med. Chem. 7:593.
Kolonin et al., 2004, “Reversal of Obesity by Targeted Ablation of Adipose Tissue,” Nature Med. 10:625.
Lauer et al., 1995, “Transfollicular Drug Delivery,” Pharm. Res. 12:179.
Lavon et al., 2004, “Ultrasound and Transdermal Drug Delivery,” Drug Discov. Today 9:679.
Li et al., 1995, “The Feasibility of Targeted Selective Gene Therapy of the Hair Follicle,” Nature Med. 1:705.
Lim et al., 2003, “Penetration Enhancement in Mouse Skin and Lipolysis in Adipocytes by TAT-GKH, a New Cosmetic Ingredient,” J. Cosmet. Sci., 54:483.
Lopes et al., 2005, “Comparative Study of the Skin Penetration of Protein Transduction Domains and a Conjugated Peptide,” Pharm. Res. 22:750.
McAllister et al., 2003, “Microfabricated Needles for Transdermal Delivery of Macromolecules and Nanoparticles: Fabrication Methods and Transport Studies,” Proc. Natl. Acad. Sci. U.S.A. 100:13755.
Meidin et al., 1998, “Low Intensity Ultrasound as a Probe to Elucidate the Relative Follicular Contribution to Total Transdermal Absorption,” Pharm. Res. 15:85.
Mitragotri et al., 1995, “Ultrasound-Mediated Transdermal Protein Delivery,” Science, 269:850.
Pasqualini et al., 1996, “Organ Targeting in vivo Using Phage Display Peptide Libraries,” Nature, 380:364.
Prausnitz et al., 2004, “Current Status and Future Potential of Transdermal Drug Delivery,” Nature, 3:115-123.
Purdon et al., 2004, “Penetration Enhancement of Transdermal Delivery—Current Permutations and Limitations,” Crit. Rev. Ther. Drug Carrier Syst. 21:97.
Raffii et al., 2003, “Tumor Vasculature Address Book: Identification of Stage-Specific Tumor Vessel Zip Codes by Phage Display,” Cancer Cell, 4:331.
Rolland et al., 1993, “Site-Specific Drug Delivery to Pilosebaceous Structures Using Polymeric Microspheres,” Pharm. Res. 10:1783.
Rothbard et al., 2000, “Conjugation of Arginine Oligomers to Cyclosporin A Facilitates Topical Delivery and Inhibition of Inflammation,” Nature Med. 6:1253.
Scheuplein et al., 1971, “Permeability of the Skin,” Physiol. Rev. 51:701.
Schutz-Redelmeier et al., 2004, “Antennapedia Transduction Sequence Promotes Anti Tumour Immunity to Epicutaneously Administered CTL Epitopes,” Vaccine 22:1985.
Sidhu et al., 2003, “Exploring Protein—Protein Interactions with Phage Display,” Chembiochem. 4:14.
Thomas et al., 2004, “The Transdermal Revolution,” Drug Discov. Today 9:697.
Weiner, 1998, “Targeted Follicular Delivery of Macromolecules via Liposomes,” Intl. Journal of Pharmaceutics, 162:29-38.
Whaley et al., 2000, “Selection of Peptides with Semiconductor Binding Specificity for Directed Nanocrystal Assembly,” Nature, 405:665.
Williams et al., 2004, “Penetration Enhancers,” Adv. Drug Deliv. Rev. 56:603.
Zaffaroni, 1991, “Overview and Evolution of Therapeutic Systems,” Ann. N.Y. Acad. Sci. 618:405.
Chen Yongping
Guo Xin
Shen Yuanyuan
Wang Weiping
Wen Long-Ping
Gupta Anish
Novomed Technologies, Inc. (Shanghai)
Sutherland & Asbill & Brennan LLP
University of Science & Technology of China
LandOfFree
Transdermal delivery peptides and method of use thereof does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Transdermal delivery peptides and method of use thereof, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Transdermal delivery peptides and method of use thereof will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4229498