Transdermal delivery of the narcotic analgesics etorphine and an

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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A61K 3144

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active

048913774

ABSTRACT:
A process for relieving pain and novel topical compositions for transdermal delivery of a narcotic analgesic comprising the application to mammalian skin of an effective amount of a compound of the formula: ##STR1## or a pharmacologically acceptable acid addition salt thereof, where R is --CH.sub.2, ##STR2## or --H and R' and R" are C.sub.1 to C.sub.6 hydrocarbons or --H, in association with a topical pharmaceutical carrier selected from the group consisting of ointments, lotions, pastes, jellies, gels, creams, sprays, aerosols and the like.

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