Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Web – sheet or filament bases; compositions of bandages; or...
Reexamination Certificate
2000-11-13
2003-05-27
Page, Thurman K. (Department: 1615)
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Web, sheet or filament bases; compositions of bandages; or...
C424S443000, C424S448000
Reexamination Certificate
active
06569449
ABSTRACT:
BACKGROUND OF THE INVENTION
1. Technical Field
The present invention relates to a composition, a method and an apparatus for transdermally delivering an effective amount of opioid antagonists derived from prodrugs for treatment of eating disorders, narcotic dependence and alcoholism. Alternatively, the present invention relates to a composition, a method and an apparatus for transdermally delivering an effective amount of an opioid antagonist derived from pro-drugs and an effective amount of an opioid agonist for treatment of pain.
2. Related Art
Opioid antagonists such as Naltrexone may be used for treatment of narcotic dependence and alcoholism. Naltrexone is currently available as Naltrexone Hydrochloride in a 50-mg oral tablet (ReVia®).
There is a need to accurately deliver effective amounts of opioid antagonists such as Naltrexone in a manner that encourages voluntary compliance when such opioid antagonists are used for the treatment of narcotic dependence and alcoholism.
SUMMARY OF THE INVENTION
The present invention provides a composition, a method and an apparatus for transdermally delivering an effective amount of opioid antagonists derived from prodrugs for treatment of narcotic dependence and alcoholism. In addition, the present invention relates to a composition, a method and an apparatus for transdermally delivering an effective amount of an opioid antagonist derived from prodrugs and an effective amount of an opioid agonist for treatment of pain.
REFERENCES:
patent: 4573995 (1986-03-01), Chen et al.
patent: 4626539 (1986-12-01), Aungst et al.
patent: 4668685 (1987-05-01), Shami
patent: 4673679 (1987-06-01), Aungst et al.
patent: 4806341 (1989-02-01), Chien et al.
patent: 4935428 (1990-06-01), Lewis
patent: 5096715 (1992-03-01), Sinclair
patent: 5149538 (1992-09-01), Granger et al.
patent: 5239714 (1993-08-01), Lee et al.
patent: 5816260 (1998-10-01), Kallman et al.
patent: 5817665 (1998-10-01), Dante
patent: 5834480 (1998-11-01), Elkhoury
patent: 5908846 (1999-06-01), Bundgaard et al.
patent: 5972954 (1999-10-01), Foss et al.
Stinchcomb Audra L.
Swaan Peter W.
Ghali Isis
Page Thurman K.
University of Kentucky Research Foundation
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