Transdermal delivery of drugs from an aqueous reservoir

Details Transdermal delivery of drugs from an aqueous reservoir Transdermal delivery of drugs from an aqueous reservoir

1987-02-24

1990-02-27

Swisher, Nancy A. B.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Web, sheet or filament bases; compositions of bandages; or...

6048921, A61K 900

Patent

active

049044753

ABSTRACT:
A transdermal delivery device for delivering drugs, typically ionized drugs, from an aqueous reservoir is described. The device comprises an aqueous drug reservoir in the form of a gel confined between an impermeable backing member and a porous support structure. In preferred embodiments the support structure is the substrate to which is applied a porous or patterned in-line adhesive. A strippable release liner is preferably provided on the adhesive while in the package. The devices are usable to deliver drugs such as chlorpheniramine maelate, brompheneiramine maleate and scopolamine hydrobromide.

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