Surgery – Controlled release therapeutic device or system – Osmotic or diffusion pumped device or system
Patent
1986-09-02
1990-07-03
Rosenbaum, C. Fred
Surgery
Controlled release therapeutic device or system
Osmotic or diffusion pumped device or system
424449, A61K 900
Patent
active
049387596
ABSTRACT:
A transdermal delivery device having a release-rate controlling-adhesive is disclosed having improved delivery characteristics. The device employs a polyisobutylene/mineral oil adhesive formulation and an ethylene/viny acetate (EVA) drug reservoir formulation. The device is useful in delivering a wide variety of transdermally administrable drugs, particularly those which are moderately soluble in mineral oil. Preferred embodiments deliver timolol base and atropine base from an EVA (40% VA) reservoir formulation.
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Journal of Macromolecular Science Review of Macromolecular Chemistry and Physics C23(1), pp. 61, 62, 85, 86 (1983).
Enscore David J.
Lee Eun S.
Yum Su I.
ALZA Corporation
Mandell Edward L.
Rose Sharon
Rosenbaum C. Fred
Sabatine Paul L.
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