Transdermal controlled delivery of pharmaceuticals at variable d

Details Transdermal controlled delivery of pharmaceuticals at variable d Transdermal controlled delivery of pharmaceuticals at variable d

1992-09-14

1998-08-04

Venkat, Jyothsan

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Web, sheet or filament bases; compositions of bandages; or...

424448, A61F 1302

Patent

active

057889830

ABSTRACT:
Transdermal polymer dosage units are provided which comprise a backing layer and a reservoir layer. The reservoir layer can have multiple regions which contact the skin during use, optionally may have different pharmaceuticals, may provide variable rate of transdermal absorption, and may provide the pharmaceuticals in the form of microreservoirs or one or more macroreservoirs. The reservoir region can comprise a macroreservoir of one or more pharmaceuticals wherein the reservoir is bounded by a backing layer and a layer of a substantially non-porous permeability-regulating polymer membrane which directly or indirectly contacts the skin during transdermal administration. Also, provided is a process of transdermal administration of pharmaceuticals using the novel dosage units.

REFERENCES:
patent: 3419578 (1968-12-01), Fitzmaurice et al.
patent: 3598122 (1971-08-01), Zaffaroni
patent: 4379454 (1983-04-01), Campbell et al.
patent: 4624665 (1986-11-01), Nuwayser
patent: 4640689 (1987-02-01), Sibalis
patent: 4666441 (1987-05-01), Andriola et al.
patent: 4687481 (1987-08-01), Nuwayser
patent: 4708746 (1987-11-01), Sibalis
patent: 4743249 (1988-05-01), Loveland
patent: 4788062 (1988-11-01), Gale et al.
patent: 4816258 (1989-03-01), Nepberge et al.
patent: 4818540 (1989-04-01), Chien et al.
patent: 4911707 (1990-03-01), Heiber et al.
patent: 4913905 (1990-04-01), Frankhauser et al.
patent: 4917688 (1990-04-01), Nelson et al.
patent: 4931281 (1990-06-01), Kim et al.
patent: 4959365 (1990-09-01), Francoeur et al.
patent: 4994049 (1991-02-01), Latzke et al.
patent: 5016652 (1991-05-01), Rose et al.
patent: 5023084 (1991-06-01), Chien et al.
patent: 5051259 (1991-09-01), Olsen et. al.
patent: 5064422 (1991-11-01), Wick
patent: 5066494 (1991-11-01), Becher
patent: 5071656 (1991-12-01), Lee et al.
patent: 5128124 (1992-07-01), Frankhauser et al.
patent: 5190962 (1993-03-01), Barberich et al.
patent: 5317009 (1994-05-01), Lee-Huang et al.
"Estrogen Replacement Therapy by Transdermal Estradiol Administration" Am. J. Obstet Gynecol, Jul., 1983, vol. 146, No. 5 (533) Laufer et al.
"Transdermal Dual-Controlled Delivery of Contraceptive Drugs: Formulation Development, in vitro and in vivo Evaluations, and Clinical Performance," Yie. W. Chien, et. al, Pharmaceutical Research, vol. 6, No. 12, 1989.

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